Hecho general: 2281 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Hecho matemático: 2281 is the exponent of a Mersenne prime.
Trivia: 2281 is an uninteresting number.
Fecha histórica: March 30th is the day in 1867 that Alaska is purchased from Russia for $7.2 million, about 2 cent/acre ($4.19/km²), by United States Secretary of State William H. Seward.